The six-party talks have begun to discuss substantive issue.

六方会谈已开始讨论实质性问题。

youdao

The issue where there is the largest substantive issue is on nuclear power.

最有实质意义的问题是核能问题。

youdao

On nearly every substantive issue, Obama scaled back American goals and expectations.

几乎在所谈论的每一个实质性问题上，奥巴马都缩减了美国的目标和期望。

youdao

Ninety percent of the United States Senate on a substantive issue, an important issue like this, is quite an accomplishment.

WHITEHOUSE: Press Briefing

He was laying out his vision on a very substantive issue -- wonky issue, if you will -- deficits, debts, spending, entitlements, interest payments, Pentagon spending.

WHITEHOUSE: Press Briefing

You know that he was talking about a substantive issue.

WHITEHOUSE: Press Briefing